Integrin beta 7 anticorps (C-Term)

N° du produit ABIN2798921

L’anticorps Lapin Polyclonal anti-Integrin beta 7 a été validé pour WB. Il convient pour détecter Integrin beta 7 dans des échantillons de Humain.

Aperçu rapide pour Integrin beta 7 anticorps (C-Term) (ABIN2798921)

Antigène: Integrin beta 7 (ITGB7)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Integrin beta 7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Integrin beta 7 anticorps

Épitope: AA 737-765, C-Term

Fonction: Rabbit Anti-Human ITGB7 (C-term) Antibody

Immunogène: This ITGB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-765 amino acids from the C-terminal region of human ITGB7.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000ITGB7 Antibody (C-term) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur Integrin beta 7

Antigène: Integrin beta 7 (ITGB7)

Autre désignation: ITGB7

Sujet:

Target Description: Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.

Gene Symbol: ITGB7

Poids moléculaire: 86903 Da

ID gène: 3695

UniProt: P26010

Pathways: Integrin Complex